Zach Cregger’s Resident Evil set for Sept. 17 release with $40–$50M opening projection

GG Brief Editorial Desk · AI-assisted, source attributed

Zach Cregger’s new live-action Resident Evil opens in theaters on September 17 and is projected to earn $40–$50 million in its North American opening weekend. The film’s roughly 95‑minute runtime lets theaters schedule more daily screenings, boosting potential ticket sales. A $40M+ debut would be the franchise’s best opening and dramatically improve on the poor box office of 2021’s Resident Evil: Welcome to Raccoon City.

• Release date and director: the film opens September 17 and is directed by Zach Cregger.
• Projected opening weekend: estimated to earn $40–$50 million in North America, which would nearly double Resident Evil: Afterlife’s $26.6 million 2010 opening.
• Runtime advantage: the movie runs about 95 minutes, enabling more showings per day to maximize ticket sales.
• Franchise context: a $40M+ opening would match Cregger’s previous film Weapons (which opened to $43.5M and later grossed $270M worldwide); the series’ top global earner remains Resident Evil: The Final Chapter at $312.2M, while 2021’s Welcome to Raccoon City made $42M total.